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    ÖÐÎÄÃû³Æ£º TRIM23 ¿¹Ô­£¨ÖØ×éµ°°×£©

    Ó¢ÎÄÃû³Æ£º TRIM23 Antigen (Recombinant Protein)

    ±ð     Ãû£º tripartite motif containing 23; ARD1; ARFD1; RNF46

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    Fusion protein corresponding to a region derived from 1-200 amino acids of human TRIM23

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    Full name:

    tripartite motif containing 23

    Synonyms:

    ARD1; ARFD1; RNF46

    Swissprot:

    P36406

    Gene Accession:

    BC022510

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described.


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