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中文名称： TMEM123 抗原（重组蛋白）
英文名称： TMEM123 Antigen (Recombinant Protein)
别 名： transmembrane protein 123; KCT3; PORMIN; PORIMIN
储 存： 冷冻（-20℃）
相关类别：抗原
概 述
|
Full name: |
transmembrane protein 123 |
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Synonyms: |
KCT3; PORMIN; PORIMIN |
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Swissprot: |
Q8N131 |
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Gene Accession: |
BC032296 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death. |
