Name: TMEM123 抗原（重组蛋白）
Brand: 通蔚生物

中文名称： TMEM123 抗原（重组蛋白）

英文名称： TMEM123 Antigen (Recombinant Protein)

别名： transmembrane protein 123; KCT3; PORMIN; PORIMIN

储存： 冷冻（-20℃）

相关类别：抗原

概述

Fusion protein corresponding to a region derived from 27-166 amino acids of human TMEM123

技术规格

Full name:	transmembrane protein 123
Synonyms:	KCT3; PORMIN; PORIMIN
Swissprot:	Q8N131
Gene Accession:	BC032296
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.

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