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    • TLE1 抗原(重组蛋白)

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      • 品牌 : 通蔚生物
      • 目录号 : TW5557
      • 应用 : 仅供科研使用
      • 货期 : 现货
      • 规格 :100ug
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    中文名称: TLE1 抗原(重组蛋白)

    英文名称:
    TLE1 Antigen (Recombinant Protein)

    别     名:
    transducin like enhancer of split 1; ESG; ESG1; GRG1

    储     存: 冷冻(-20℃)

    相关类别:抗原

    概     述

    Fusion protein corresponding to a region derived from 571-770 amino acids of human TLE1

    技术规格

    Full name:

    transducin like enhancer of split 1

    Synonyms:

    ESG; ESG1; GRG1

    Swissprot:

    Q04724

    Gene Accession:

    BC015747

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.


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