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中文名称： KLK6 抗原（重组蛋白）
英文名称： KLK6 Antigen (Recombinant Protein)
别 名： kallikrein-related peptidase 6; hK6; Bssp; Klk7; SP59; PRSS9; PRSS18
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述
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Fusion protein corresponding to a region derived from 22-244 amino acids of human KLK6 |
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Full name: |
kallikrein-related peptidase 6 |
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Synonyms: |
hK6; Bssp; Klk7; SP59; PRSS9; PRSS18 |
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Swissprot: |
Q92876 |
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Gene Accession: |
BC015525 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene. |
