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    ÖÐÎÄÃû³Æ£º SENP5 ¿¹Ô­£¨ÖØ×éµ°°×£©

    Ó¢ÎÄÃû³Æ£º SENP5 Antigen (Recombinant Protein)

    ±ð     Ãû£º SUMO specific peptidase 5

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    Fusion protein corresponding to a region derived from 551-755 amino acids of human SENP5

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    Full name:

    SUMO specific peptidase 5

    Swissprot:

    Q96HI0

    Gene Accession:

    BC030705

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).


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