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中文名称：兔抗CDK2AP1多克隆抗体
英文名称： Anti-CDK2AP1 rabbit polyclonal antibody
别 名： cyclin dependent kinase 2 associated protein 1; DOC1; ST19; DORC1; doc-1; p12DOC-1
储 存： 冷冻（-20℃）
宿 主： Rabbit
抗 原： CDK2AP1
反应种属： Human, Mouse
标 记 物： Unconjugate
克隆类型： rabbit polyclonal
技术规格
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Background: |
The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
CDK2AP1 |
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Immunogen: |
Full length fusion protein |
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Full name: |
cyclin dependent kinase 2 associated protein 1 |
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Synonyms: |
DOC1; ST19; DORC1; doc-1; p12DOC-1 |
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SwissProt: |
O14519 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human liver cancer |
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IHC Recommend dilution: |
25-100 |
