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ÖÐÎÄÃû³Æ£º  Íÿ¹MPZL1¶à¿Ë¡¿¹Ìå


Ó¢ÎÄÃû³Æ£º  Anti-MPZL1 rabbit polyclonal antibody


±ð      Ãû£º  myelin protein zero like 1; PZR; PZRa; PZRb; PZR1b; MPZL1b


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ËÞ      Ö÷£º  Rabbit


¿¹      Ô­£º  MPZL1


·´Ó¦ÖÖÊô£º  Human, Mouse, Rat


±ê  ¼Ç  Î  Unconjugate


¿Ë¡ÀàÐÍ£º  rabbit polyclonal


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Background:

Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.

Applications:

ELISA, IHC

Name of antibody:

MPZL1

Immunogen:

Fusion protein of human MPZL1

Full name:

myelin protein zero like 1

Synonyms:

PZR; PZRa; PZRb; PZR1b; MPZL1b

SwissProt:

O95297

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil and Human brain

IHC Recommend dilution:

20-100





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