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中文名称：兔抗ZBTB44多克隆抗体
技术规格
Background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 44 (ZBTB44), also known as BTBD15, is a 570 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB44 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB44 functions as a transcription regulator. Four isoforms of ZBTB44 have been identified.
Applications:
ELISA, IHC
Name of antibody:
ZBTB44
Immunogen:
Fusion protein of human ZBTB44
Full name:
zinc finger and BTB domain containing 44
Synonyms:
BTBD15; ZNF851; HSPC063
SwissProt:
Q8NCP5
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human thyroid cancer and human colorectal cancer
IHC Recommend dilution:
30-150
