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    • Íÿ¹APPL1¶à¿Ë¡¿¹Ìå

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    ÖÐÎÄÃû³Æ£ºÍÿ¹APPL1¶à¿Ë¡¿¹Ìå

    Ó¢ÎÄÃû³Æ£º Anti-APPL1 rabbit polyclonal antibody

    ±ð      Ãû£º APPL; DIP13alpha

    ´¢      ´æ£º Àä¶³£¨-20¡æ£©

    ¿¹      Ô­£º APPL1

    ËÞ      Ö÷£º Rabbit

    Ïà¹ØÀà±ð£º Ò»¿¹

    ·´Ó¦ÖÖÊô£º Human, Mouse

    ±ê ¼Ç Î Unconjugate

    ¿Ë¡ÀàÐÍ£º rabbit polyclonal

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    Background:

    The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.

    Applications:

    ELISA, WB, IHC

    Name of antibody:

    APPL1

    Immunogen:

    Fusion protein of human APPL1

    Full name:

    Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1

    Synonyms£º

    APPL; DIP13alpha

    SwissProt:

    Q9UKG1

    ELISA Recommended dilution:

    2000-5000

    IHC positive control:

    Human esophagus cancer and human lung cancer

    IHC Recommend dilution:

    100-300

    WB Predicted band size:

    80 kDa

    WB Positive control:

    A172 cells

    WB Recommended dilution:

    500-2000





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