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021-54845833/15800441009
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Background: |
This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation. DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
DDAH1 |
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Immunogen: |
Synthetic peptide of human DDAH1 |
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Full name: |
dimethylarginine dimethylaminohydrolase 1 |
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Synonyms： |
DDAH |
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SwissProt: |
O94760 |
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ELISA Recommended dilution: |
1000-5000 |
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IHC positive control: |
Human thyroid cancer and Human brain |
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IHC Recommend dilution: |
50-200 |
