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      ÖÐÎÄÃû³Æ£º  Íÿ¹MCM2¶à¿Ë¡¿¹Ìå


      Ó¢ÎÄÃû³Æ£º  Anti-MCM2 rabbit polyclonal antibody


      ±ð       Ãû£º  BM28; CCNL1; CDCL1; cdc19; D3S3194; MITOTIN


      ¿¹       Ô­£º  MCM2


      ´¢       ´æ£º  Àä¶³£¨-20¡æ£©

       

      ËÞ      Ö÷£º  Rabbit


      Ïà¹ØÀà±ð£º Ò»¿¹


      ·´Ó¦ÖÖÊô£º Human, Mouse

      ±ê  ¼Ç Î Unconjugate


      ¿Ë¡ÀàÐÍ£º rabbit polyclonal


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      Background:

      The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.

      Applications:

      ELISA, WB, IHC

      Name of antibody:

      MCM2

      Immunogen:

      Fusion protein of human MCM2

      Full name:

      minichromosome maintenance complex component 2

      Synonyms£º

      BM28; CCNL1; CDCL1; cdc19; D3S3194; MITOTIN

      SwissProt:

      P49736

      ELISA Recommended dilution:

      2000-5000

      IHC positive control:

      Human lung cancer

      IHC Recommend dilution:

      25-100

      WB Predicted band size:

      102 kDa

      WB Positive control:

      293T, hela, K562, Raji and 231 cells

      WB Recommended dilution:

      500-2000







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