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    • Íÿ¹IBA57¶à¿Ë¡¿¹Ìå

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    ÖÐÎÄÃû³Æ£º Íÿ¹IBA57¶à¿Ë¡¿¹Ìå

    Ó¢ÎÄÃû³Æ£º Anti-IBA57 rabbit polyclonal antibody

    ±ð     Ãû£º MMDS3; SPG74; C1orf69

    Ïà¹ØÀà±ð£º Ò»¿¹

    ´¢     ´æ£º Àä¶³£¨-20¡æ£©

    ËÞ     Ö÷£º Rabbit

    ¿¹     Ô­£º IBA57

    ·´Ó¦ÖÖÊô£º Human

    ±ê ¼Ç Î Unconjugate

    ¿Ë¡ÀàÐÍ£º rabbit polyclonal


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    Background:

    The protein encoded by this gene localizes to the mitochondrion and is part of the iron-sulfur cluster assembly pathway. The encoded protein functions late in the biosynthesis of mitochondrial 4Fe-4S proteins. Defects in this gene have been associated with autosomal recessive spastic paraplegia-74 and with multiple mitochondrial dysfunctions syndrome-3. Two transcript variants encoding different isoforms have been found for this gene. The smaller isoform is not likely to be localized to the mitochondrion since it lacks the amino-terminal transit peptide.

    Applications:

    ELISA, IHC

    Name of antibody:

    IBA57

    Immunogen:

    Synthetic peptide of human IBA57

    Full name:

    IBA57 homolog, iron-sulfur cluster assembly

    Synonyms:

    MMDS3; SPG74; C1orf69

    SwissProt:

    Q5T440

    ELISA Recommended dilution:

    5000-10000

    IHC positive control:

    Human ovarian cancer and human brain

    IHC Recommend dilution:

    30-150












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