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中文名称：兔抗ARNT2多克隆抗体
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Background: |
This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively. |
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Applications: |
WB |
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Name of antibody: |
ARNT2 |
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Immunogen: |
Synthesized peptide derived from internal of human ARNT2. |
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Full name: |
aryl-hydrocarbon receptor nuclear translocator 2 |
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Synonyms： |
WEDAS; bHLHe1 |
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SwissProt: |
Q9HBZ2 |
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WB Predicted band size: |
79 kDa |
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WB Positive control: |
Jurkat cells and 293 cells lysates |
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WB Recommended dilution: |
500-3000 |
