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    • Íÿ¹MAN1B1¶à¿Ë¡¿¹Ìå

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    ÖÐÎÄÃû³Æ£º Íÿ¹MAN1B1¶à¿Ë¡¿¹Ìå


    Ó¢ÎÄÃû³Æ£º Anti-MAN1B1 rabbit polyclonal antibody


    ±ð       Ãû£º  mannosidase alpha class 1B member 1; MRT15; ERMAN1; ERManI; MANA-ER


    ´¢       ´æ£º  Àä¶³£¨-20¡æ£©


    ¿¹      Ô­£º  MAN1B1


    ËÞ      Ö÷£º  Rabbit


    Ïà¹ØÀà±ð£º Ò»¿¹


    ·´Ó¦ÖÖÊô£º Human, Mouse, Rat


    ±ê  ¼Ç  Î  Unconjugate


    ¿Ë¡ÀàÐÍ£º rabbit polyclonal


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    Background:

    This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11.

    Applications:

    ELISA, IHC

    Name of antibody:

    MAN1B1

    Immunogen:

    Fusion protein of human MAN1B1

    Full name:

    mannosidase alpha class 1B member 1

    Synonyms:

    MRT15; ERMAN1; ERManI; MANA-ER

    SwissProt:

    Q9UKM7

    ELISA Recommended dilution:

    5000-10000

    IHC positive control:

    Human prostate cancer

    IHC Recommend dilution:

    50-200




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