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Ó¢ÎÄÃû³Æ£º Anti-MAN1B1 rabbit polyclonal antibody
±ð Ãû£º mannosidase alpha class 1B member 1; MRT15; ERMAN1; ERManI; MANA-ER
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¿¹ Ô£º MAN1B1
ËÞ Ö÷£º Rabbit
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·´Ó¦ÖÖÊô£º Human, Mouse, Rat
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
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Background:
This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11.
Applications:
ELISA, IHC
Name of antibody:
MAN1B1
Immunogen:
Fusion protein of human MAN1B1
Full name:
mannosidase alpha class 1B member 1
Synonyms:
MRT15; ERMAN1; ERManI; MANA-ER
SwissProt:
Q9UKM7
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human prostate cancer
IHC Recommend dilution:
50-200

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021-54845833/15800441009
