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Ó¢ÎÄÃû³Æ£º SERPINB3 Antigen (Recombinant Protein)

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Fusion protein corresponding to a region derived from 257-390 amino acids of human SERPINB3

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Full name:

serpin peptidase inhibitor, clade B (ovalbumin), member 3

Synonyms:

SCC; T4-A; SCCA1; SCCA-1; HsT1196; SCCA-PD

Swissprot:

P29508

Gene Accession:

BC005224

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

SERPINB3(serpin peptidase inhibitor, clade B (ovalbumin), member 3), also known as SCCA1, increase in advancing stages of some cervical, lung, esophageal and head and neck cancers). Human chromosome position 18q21.3 contains a cluster of serpins, including a tandem duplication of the SCCA gene, plasminogen activator inhibitor type 2, and maspin. SCCA is transcribed by two nearly identical genes (SCCA1 and SCCA2), and is mainly produced as SCCA1. The human SCCA1 gene encodes a 390 amino acid protein that was originally isolated from a metastatic cervical squamous cell carcinoma.


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