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中文名称：SETMAR抗原（重组蛋白）
英文名称： SETMAR Antigen (Recombinant Protein)
别 名： Mar1; METNASE
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 14-213 amino acids of human SETMAR |
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Full name: |
SET domain and mariner transposase fusion gene |
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Synonyms: |
Mar1; METNASE |
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Swissprot: |
Q53H47 |
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Gene Accession: |
BC011635 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. |
