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Fusion protein corresponding to a region derived from 332-538 amino acids of human RBBP5 |
技术规格
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Full name: |
retinoblastoma binding protein 5 |
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Synonyms: |
RBQ3; SWD1 |
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Swissprot: |
Q15291 |
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Gene Accession: |
BC053856 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. |
