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中文名称：兔抗BRAF(Phospho-Ser446)多克隆抗体
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Background: |
This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. |
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Applications: |
WB |
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Name of antibody: |
BRAF(Phospho-Ser446) |
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Immunogen: |
Peptide sequence around phosphorylation site of Serine 446 (R-D-S(p)-S-D) derived from Human B-RAF. |
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Full name: |
B-Raf proto-oncogene, serine/threonine kinase |
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Synonyms： |
NS7; BRAF1; RAFB1; B-RAF1 |
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SwissProt: |
P15056 |
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WB Predicted band size: |
84 kDa |
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WB Positive control: |
293 cells lysates treated with EGF |
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WB Recommended dilution: |
500-1000 |
