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ÖÐÎÄÃû³Æ£º СÊó¿¹SIRT6µ¥¿Ë¡¿¹Ìå

Ó¢ÎÄÃû³Æ£º Anti-SIRT6 mouse monoclonal antibody

±ð    Ãû£º sirtuin 6; SIR2L6

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´¢    ´æ£º Àä¶³£¨-20¡æ£©

ËÞ    Ö÷£º Mouse

¿¹    Ô­£º SIRT6

·´Ó¦ÖÖÊô£º Human, Mouse, Rat, Monkey

±ê ¼Ç Î Unconjugate

¿Ë¡ÀàÐÍ£º Mouse Monoclonal

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Background:

This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms.

Applications:

WB, IF, IP

Name of antibody:

SIRT6

Immunogen:

Fusion protein of human SIRT6

Full name:

sirtuin 6

Synonyms:

SIR2L6

SwissProt:

Q8N6T7

WB Predicted band size:

39 kDa

WB Positive control:

Jurkat, MCF7, HCT116, K562, COS7, C2C12, 3T3 and Hela cell lysates

WB Recommended dilution:

500-2000

IF positive control:

Hela cells









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