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021-54845833/15800441009
中文名称：兔抗ATP6V0A1多克隆抗体
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Background: |
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three A subunit proteins and the encoded protein is associated with clathrin-coated vesicles. Three transcript variants encoding different isoforms have been found for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
ATP6V0A1 |
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Immunogen: |
Fusion protein of human ATP6V0A1 |
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Full name: |
ATPase H+ transporting V0 subunit a1 |
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Synonyms: |
a1; Stv1; VPP1; Vph1; ATP6N1; ATP6N1A |
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SwissProt: |
Q93050 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human liver cancer |
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IHC Recommend dilution: |
150-300 |
