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021-54845833/15800441009
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Background: |
The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
EDA |
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Immunogen: |
Fusion protein of human EDA |
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Full name: |
ectodysplasin A |
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Synonyms： |
ED1; HED; EDA1; EDA2; HED1; ODT1; XHED; ECTD1; XLHED; ED1-A1; ED1-A2; EDA-A1; EDA-A2; STHAGX1 |
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SwissProt: |
Q92838 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human lung cancer |
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IHC Recommend dilution: |
50-200 |
