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Ó¢ÎÄÃû³Æ£º Anti-PLCG1(Ab-771) rabbit polyclonal antibody
±ð Ãû£º phospholipase C, gamma 1
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ËÞ Ö÷£º Rabbit
¿¹ Ô£º PLCG1(Ab-771)
·´Ó¦ÖÖÊô£º Human Mouse Rat
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º Unconjugate
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Background: |
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. |
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Applications: |
WB, IHC |
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Name of antibody: |
PLCG1(Ab-771) |
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Immunogen: |
Synthesized non-phosphopeptide derived from human PLCG1 around the phosphorylation site of tyrosine 771 (P-D-Y-G-A). |
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Full name: |
phospholipase C, gamma 1 |
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Synonyms£º |
phospholipase C, gamma 1 |
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SwissProt: |
P19174 |
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IHC positive control: |
Human breast carcinoma tissue |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
149 kDa |
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WB Positive control: |
COS7 cells treated with EGF (200ng/ml, 30min) lysate |
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WB Recommended dilution: |
500-3000 |


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