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021-54845833/15800441009
中文名称：兔抗ATG4D多克隆抗体
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Background: |
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
ATG4D |
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Immunogen: |
Fusion protein of human ATG4D |
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Full name: |
autophagy related 4D, cysteine peptidase |
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Synonyms： |
APG4D; AUTL4; APG4-D |
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SwissProt: |
Q86TL0 |
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ELISA Recommended dilution: |
1000-5000 |
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IHC positive control: |
Human thyroid cancer and human liver cancer |
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IHC Recommend dilution: |
50-200 |
