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ÖÐÎÄÃû³Æ£ºÍÿ¹RASGEF1A¶à¿Ë¡¿¹Ìå 

Ó¢ÎÄÃû³Æ£º Anti-RASGEF1A rabbit polyclonal antibody

±ð      Ãû£º CG4853

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´¢      ´æ£º Àä¶³£¨-20¡æ£©

ËÞ      Ö÷£º Rabbit

¿¹      Ô­£º RASGEF1A

·´Ó¦ÖÖÊô£º Human

±ê¼ÇÎ Unconjugate

¿Ë¡ÀàÐÍ£º rabbit polyclonal

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Background:

RASGEF1A (RasGEF domain family, member 1A) is a 481 amino acid guanine-nucleotide exchange factor (GEF) for H-Ras, K-Ras, and N-Ras. RASGEF1A may also play a role in cell migration. RASFEG1A is highly expressed in spinal chord and brain and contains one N-terminal Ras-GEF domain and one Ras-GEF domain. The gene that encodes RASGEF1A maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome.

Applications:

ELISA, IHC

Name of antibody:

RASGEF1A

Immunogen:

Fusion protein of human RASGEF1A

Full name:

RasGEF domain family, member 1A

Synonyms£º

CG4853

SwissProt:

Q8N9B8

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human breast cancer and human thyroid cancer

IHC Recommend dilution:

20-100



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