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    ÖÐÎÄÃû³Æ£ºÍÿ¹RASGEF1A¶à¿Ë¡¿¹Ìå 

    Ó¢ÎÄÃû³Æ£º Anti-RASGEF1A rabbit polyclonal antibody

    ±ð      Ãû£º CG4853

    Ïà¹ØÀà±ð£º Ò»¿¹

    ´¢      ´æ£º Àä¶³£¨-20¡æ£©

    ËÞ      Ö÷£º Rabbit

    ¿¹      Ô­£º RASGEF1A

    ·´Ó¦ÖÖÊô£º Human

    ±ê¼ÇÎ Unconjugate

    ¿Ë¡ÀàÐÍ£º rabbit polyclonal

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    Background:

    RASGEF1A (RasGEF domain family, member 1A) is a 481 amino acid guanine-nucleotide exchange factor (GEF) for H-Ras, K-Ras, and N-Ras. RASGEF1A may also play a role in cell migration. RASFEG1A is highly expressed in spinal chord and brain and contains one N-terminal Ras-GEF domain and one Ras-GEF domain. The gene that encodes RASGEF1A maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome.

    Applications:

    ELISA, IHC

    Name of antibody:

    RASGEF1A

    Immunogen:

    Fusion protein of human RASGEF1A

    Full name:

    RasGEF domain family, member 1A

    Synonyms£º

    CG4853

    SwissProt:

    Q8N9B8

    ELISA Recommended dilution:

    2000-5000

    IHC positive control:

    Human breast cancer and human thyroid cancer

    IHC Recommend dilution:

    20-100



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