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Background: |
Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion (By similarity). |
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Applications: |
ELISA, IHC |
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Name of antibody: |
SWAP70 |
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Immunogen: |
Fusion protein of human SWAP70 |
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Full name: |
SWAP switching B-cell complex 70kDa subunit |
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Synonyms： |
HSPC321; SWAP-70 |
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SwissProt: |
Q9UH65 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human prostate cancer and human tonsil |
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IHC Recommend dilution: |
25-100 |
