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021-54845833/15800441009
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Background: |
SPINK7 (serine peptidase inhibitor, Kazal type 7), also known as Ecg2 (esophagus cancer-related gene 2 protein), is a 76 amino acid secreted protein. Containing one Kazal-like domain, SPINK7 is thought to be a serine protease inhibitor. The gene that encodes SPINK7 maps to human chromosome 5, which contains 181 million base pairs encoding around 1,000 genes. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.Probable serine protease inhibitor. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
SPINK7 |
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Immunogen: |
Synthetic peptide of human SPINK7 |
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Full name: |
serine peptidase inhibitor, Kazal type 7 (putative) |
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Synonyms： |
ECG2; ECRG2 |
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SwissProt: |
P58062 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human prostate cancer and Human lung cancer |
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IHC Recommend dilution: |
25-100 |
