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中文名称： 兔抗PIK3R3多克隆抗体
英文名称： Anti-PIK3R3 rabbit polyclonal antibody
别 名： p55; p55-GAMMA
相关类别： 一抗
储 存： 冷冻（-20℃）
宿 主： Rabbit
抗 原： PIK3R3
反应种属： Human, Mouse, Rat
标 记 物： Unconjugate
克隆类型： rabbit polyclonal
技术规格
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Background: |
Phosphatidylinositol 3-kinase is a lipid kinase that phosphorylates the inositol ring of phosphatidylinositol and related compounds at the 3’ position. PI 3-kinase p55 (PIK3R3) is comprised of a catalytic subunit and a regulatory subunit. The human p55 protein is composed of a rare amino terminal region followed by a proline-rich motif and two Src homology 2 (SH2) domains. PI 3-kinase p55 mRNAs are expressed in most human fetal and adult tissues; predominant expression is observed in the adult testis. Splice variant(s) of PI 3-kinase p55 have been identified; one of which has a deletion of 36 amino acids at the amino terminus and another which has an insertion of 59 amino acids at position 256 between the SH2 domains. Research suggests that PI 3-kinase p55 interacts with the IGFIR (Insulin-like growth factor-I receptor) and IR (Insulin receptor) and may be involved in PI 3-kinase activation by these receptors. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
PIK3R3 |
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Immunogen: |
Synthetic peptide of human PIK3R3 |
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Full name: |
phosphoinositide-3-kinase, regulatory subunit 3 (gamma) |
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Synonyms： |
p55; p55-GAMMA |
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SwissProt: |
Q92569 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human lung cancer and Human gastric cancer |
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IHC Recommend dilution: |
25-100 |
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WB Predicted band size: |
54 kDa |
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WB Positive control: |
Mouse brain, human fetal brain and mouse testis tissue, hela cells and human fetal kidney tissue |
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WB Recommended dilution: |
500-2000 |
