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中文名称： 兔抗PRNP多克隆抗体
英文名称： Anti-PRNP rabbit polyclonal antibody
别 名： CJD; GSS; PrP; ASCR; KURU; PRIP; PrPc; CD230; AltPrP; p27-30; PrP27-30; PrP33-35C
抗 原： PRNP
相关类别： 一抗
储 存： 冷冻（-20℃）
宿 主： Rabbit
反应种属： Human, Mouse, Rat
标 记 物： Unconjugate
克隆类型： rabbit polyclonal
技术规格
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Background: |
The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
PRNP |
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Immunogen: |
Fusion protein of human PRNP |
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Full name: |
prion protein |
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Synonyms： |
CJD; GSS; PrP; ASCR; KURU; PRIP; PrPc; CD230; AltPrP; p27-30; PrP27-30; PrP33-35C |
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SwissProt: |
P04156 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human brain and human breast cancer |
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IHC Recommend dilution: |
25-100 |
