ÖÐÎÄÃû³Æ£º Íÿ¹PAK2(Ab-192) ¶à¿Ë¡¿¹Ìå
Ó¢ÎÄÃû³Æ£º Anti-PAK2(Ab-192) rabbit polyclonal antibody
±ð Ãû£º PAK65; PAKgamma
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ËÞ Ö÷£º Rabbit
¿¹ Ô£º PAK2(Ab-192)
·´Ó¦ÖÖÊô£º Human
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
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Background: |
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. |
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Applications: |
WB |
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Name of antibody: |
PAK2(Ab-192) |
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Immunogen: |
Synthesized non-phosphopeptide derived from human PAK2 around the phosphorylation site of serine 192 (T-K-S(p)-I-Y). |
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Full name: |
p21 protein (Cdc42/Rac)-activated kinase 2 |
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Synonyms£º |
PAK65; PAKgamma |
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SwissProt: |
Q13177 |
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WB Predicted band size: |
58 kDa |
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WB Positive control: |
HepG2 cells treated with serum (20%, 15mins) lysate |
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WB Recommended dilution: |
500-3000 |

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