购物车
帮助
021-54845833/15800441009
中文名称：兔抗ROCK2多克隆抗体
英文名称： Anti-ROCK2 rabbit polyclonal antibody
别 名： ROCK-II
抗 原： ROCK2
储 存： 冷冻（-20℃）
宿 主： Rabbit
相关类别： 一抗
反应种属： Human, Mouse, Rat
标记物： Unconjugate
克隆类型： rabbit polyclonal
技术规格
|
Background: |
The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP300, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4. |
|
Applications: |
ELISA, IHC |
|
Name of antibody: |
ROCK2 |
|
Immunogen: |
Fusion protein of human ROCK2 |
|
Full name: |
Rho-associated, coiled-coil containing protein kinase 2 |
|
Synonyms： |
ROCK-II |
|
SwissProt: |
O75116 |
|
ELISA Recommended dilution: |
2000-5000 |
|
IHC positive control: |
Human cervical cancer and human ovarian cancer |
|
IHC Recommend dilution: |
25-100 |
