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Background: |
Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. |
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Applications: |
WB, IHC, IF |
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Name of antibody: |
FOXO4 (Phospho-Ser197) |
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Immunogen: |
Synthetic peptide of human FOXO4 (Phospho-Ser197) |
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Full name: |
forkhead box O4 (Phospho-Ser197) |
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Synonyms： |
AFX; AFX1; MLLT7 |
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SwissProt: |
P98177 |
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IHC positive control: |
Human breast carcinoma |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
54 kDa |
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WB Positive control: |
293 cells untreated or treated with serum |
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WB Recommended dilution: |
500-1000 |
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IF Positive control: |
MCF7 cells |
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IF Recommended dilution |
100-200 |
