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Ó¢ÎÄÃû³Æ£º Anti-OAS2 rabbit polyclonal antibody
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ËÞ Ö÷£º Rabbit
¿¹ Ô£º OAS2
·´Ó¦ÖÖÊô£º Human, Mouse
±ê ¼Ç Î Unconjugate
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Background: |
This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
OAS2 |
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Immunogen: |
Fusion protein of human OAS2 |
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Full name: |
2'-5'-oligoadenylate synthetase 2 |
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SwissProt: |
P29728 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human tonsil and Human liver cancer |
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IHC Recommend dilution: |
50-200 |
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WB Predicted band size: |
82 kDa |
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WB Positive control: |
A375, RAW264.7, MC3T3-E1 cell lysates |
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WB Recommended dilution: |
200-1000 |



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