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Background: |
This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. |
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Applications: |
WB |
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Name of antibody: |
ESR2(Phospho-Ser105) |
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Immunogen: |
Peptide sequence around phosphorylation site of serine105(Q-R-S(p)-P-W) derived from Human Estrogen Receptor- beta. |
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Full name: |
estrogen receptor 2 (ER beta) |
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Synonyms： |
Erb; ESRB; ESTRB; NR3A2; ER-BETA; ESR-BETA |
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SwissProt: |
Q92731 |
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WB Predicted band size: |
59 kDa |
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WB Positive control: |
HepG2 cells lysates |
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WB Recommended dilution: |
500-1000 |
