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Background: |
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
SNX15 |
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Immunogen: |
Fusion protein of human SNX15 |
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Full name: |
sorting nexin 15 |
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Synonyms： |
HSAF001435 |
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SwissProt: |
Q9NRS6 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human esophagus cancer and human liver cancer |
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IHC Recommend dilution: |
20-100 |
