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021-54845833/15800441009
中文名称 : 小鼠抗CD3E单克隆抗体
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Background: |
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]. |
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Applications: |
WB, IHC, IF |
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Name of antibody: |
CD3E |
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Immunogen: |
Fusion protein of human CD3E |
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Full name: |
CD3e molecule, epsilon (CD3-TCR complex) (CD3E) |
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Synonyms: |
IMD18; T3E; TCRE |
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SwissProt: |
P07766 |
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IHC positive control: |
human liver tissue and human lymphoma tissue |
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IHC Recommend dilution: |
30-150 |
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WB Predicted band size: |
23 kDa |
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WB Positive control: |
COS7, Jurkat, MDCK cell lysates |
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WB Recommended dilution: |
200-1000 |
