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ÖÐÎÄÃû³Æ£º  Íÿ¹SETMAR¶à¿Ë¡¿¹Ìå  

Ó¢ÎÄÃû³Æ£º Anti-SETMAR rabbit polyclonal antibody

±ð    Ãû£º SET domain and mariner transposase fusion gene; Mar1; METNASE

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ËÞ    Ö÷£º Rabbit

¿¹    Ô­£º SETMAR

·´Ó¦ÖÖÊô£º Human, Mouse

±ê ¼Ç Î Unconjugate

¿Ë¡ÀàÐÍ£º rabbit polyclonal

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Background:

This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

SETMAR

Immunogen:

Fusion protein of human SETMAR

Full name:

SET domain and mariner transposase fusion gene

Synonyms:

Mar1; METNASE

SwissProt:

Q53H47

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer

IHC Recommend dilution:

50-300




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