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Ó¢ÎÄÃû³Æ£º Anti-SETD2 rabbit polyclonal antibody
±ð Ãû£º HYPB; SET2; HIF-1; HIP-1; KMT3A; HBP231; HSPC069; p231HBP
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¿¹ Ô£º SETD2
´¢ ´æ£º Àä¶³£¨-20¡æ£©
ËÞ Ö÷£º Rabbit
·´Ó¦ÖÖÊô£º Human, Mouse
±ê¼ÇÎ Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
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Background: |
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
SETD2 |
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Immunogen: |
Fusion protein of human SETD2 |
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Full name: |
SET domain containing 2 |
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Synonyms£º |
HYPB; SET2; HIF-1; HIP-1; KMT3A; HBP231; HSPC069; p231HBP |
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SwissProt: |
Q9BYW2 |
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ELISA Recommended dilution: |
1000-5000 |
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IHC positive control: |
Human tonsil and human cervical cancer |
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IHC Recommend dilution: |
50-200 |
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021-54845833/15800441009
