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ÖÐÎÄÃû³Æ£º  Íÿ¹SCNN1A¶à¿Ë¡¿¹Ìå 

Ó¢ÎÄÃû³Æ£º Anti-SCNN1A rabbit polyclonal antibody

±ð    Ãû£º BESC2; ENaCa; SCNEA; SCNN1; ENaCalpha

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ËÞ    Ö÷£º Rabbit

¿¹    Ô­£º SCNN1A

·´Ó¦ÖÖÊô£º Human

±ê ¼Ç Î Unconjugate

¿Ë¡ÀàÐÍ£º rabbit polyclonal

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Background:

Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Applications:

ELISA, IHC

Name of antibody:

SCNN1A

Immunogen:

Synthetic peptide of human SCNN1A

Full name:

sodium channel, non-voltage-gated 1 alpha subunit

Synonyms£º

BESC2; ENaCa; SCNEA; SCNN1; ENaCalpha

SwissProt:

P37088

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human thyroid cancer and Human colon cancer

IHC Recommend dilution:

25-100



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