ÖÐÎÄÃû³Æ£º Íÿ¹SCNN1A¶à¿Ë¡¿¹Ìå
Ó¢ÎÄÃû³Æ£º Anti-SCNN1A rabbit polyclonal antibody
±ð Ãû£º BESC2; ENaCa; SCNEA; SCNN1; ENaCalpha
Ïà¹ØÀà±ð£º Ò»¿¹
´¢ ´æ£º Àä¶³£¨-20¡æ£©
ËÞ Ö÷£º Rabbit
¿¹ Ô£º SCNN1A
·´Ó¦ÖÖÊô£º Human
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
¼¼Êõ¹æ¸ñ
|
Background: |
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
|
Applications: |
ELISA, IHC |
|
Name of antibody: |
SCNN1A |
|
Immunogen: |
Synthetic peptide of human SCNN1A |
|
Full name: |
sodium channel, non-voltage-gated 1 alpha subunit |
|
Synonyms£º |
BESC2; ENaCa; SCNEA; SCNN1; ENaCalpha |
|
SwissProt: |
P37088 |
|
ELISA Recommended dilution: |
2000-5000 |
|
IHC positive control: |
Human thyroid cancer and Human colon cancer |
|
IHC Recommend dilution: |
25-100 |
¹ºÎï³µ
°ïÖú
021-54845833/15800441009
