购物车
帮助
021-54845833/15800441009中文名称：兔抗RUNX1(Ab-435) 多克隆抗体
英文名称： Anti-RUNX1(Ab-435) rabbit polyclonal antibody
别 名： AML1; CBFA2; EVI-1; AMLCR1; PEBP2aB; AML1-EVI-1
相关类别： 一抗
储 存： 冷冻（-20℃） 避光
抗 原： RUNX1(Ab-435)
宿 主： Rabbit
反应种属： Human
标记物： Unconjugate
克隆类型： rabbit polyclonal
技术规格
|
Background: |
CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. The alpha subunit binds DNA and appears to have a role in the development of normal hematopoiesis. Isoform AML-1L interferes with the transactivation activity of RUNX1. Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the mouse BLK promoter. Inhibits KAT6B-dependent transcriptional activation. |
|
Applications: |
WB |
|
Name of antibody: |
RUNX1(Ab-435) |
|
Immunogen: |
Synthesized non-phosphopeptide derived from human AML1 around the phosphorylation site of serine 435 (S-N-S(p)-P-T). |
|
Full name: |
runt-related transcription factor 1 |
|
Synonyms： |
AML1; CBFA2; EVI-1; AMLCR1; PEBP2aB; AML1-EVI-1 |
|
SwissProt: |
Q01196 |
|
WB Predicted band size: |
49 kDa |
|
WB Positive control: |
HepG2 cells treated with PMA (125ng/ml, 30mins) lysate |
|
WB Recommended dilution: |
500-3000 |
