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  • Íÿ¹PIK3R5¶à¿Ë¡¿¹Ìå

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    • Æ·ÅÆ : ͨεÉúÎï
    • Ŀ¼ºÅ : TW21671
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ÖÐÎÄÃû³Æ :   Íÿ¹PIK3R5¶à¿Ë¡¿¹Ìå


Ó¢ÎÄÃû³Æ :    Anti-PIK3R5 rabbit polyclonal antibody


±ð        Ãû :   p101; FOAP-2; P101-PI3K; F730038I15Rik


´¢        ´æ :   Àä¶³£¨-20¡æ£© ±Ü¹â


¿¹       Ô­ :   PIK3R5


ËÞ       Ö÷ :   Rabbit


·´Ó¦ÖÖÊô :   Human Mouse


Ïà¹ØÀà±ð :   Ò»¿¹


±ê  ¼Ç  Îï :   Unconjugate


¿Ë¡ÀàÐÍ :   rabbit polyclonal


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Background:

Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found.

Applications:

IHC

Name of antibody:

PIK3R5

Immunogen:

Synthesized peptide derived from internal of human PIK3R5.

Full name:

phosphoinositide-3-kinase, regulatory subunit 5

Synonyms£º

p101; FOAP-2; P101-PI3K; F730038I15Rik

SwissProt:

Q8WYR1

IHC positive control:

Human colon carcinoma tissue

IHC Recommend dilution:

50-100






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