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    • Íÿ¹UBXN1¶à¿Ë¡¿¹Ìå

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    ÖÐÎÄÃû³Æ£º Íÿ¹UBXN1¶à¿Ë¡¿¹Ìå

    Ó¢ÎÄÃû³Æ£º Anti-UBXN1 rabbit polyclonal antibody

    ±ð      Ãû£º UBX domain protein 1; 2B28; SAKS1; UBXD10

    Ïà¹ØÀà±ð£º Ò»¿¹

    ´¢       ´æ£º Àä¶³£¨-20¡æ£©

    ËÞ       Ö÷£º Rabbit

    ¿¹       Ô­£º UBXN1

    ·´Ó¦ÖÖÊô£º Human, Mouse, Rat

    ±ê   ¼Ç Î Unconjugate

    ¿Ë¡ÀàÐÍ£º rabbit polyclonal

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    Background:

    Ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.

    Applications:

    ELISA, WB, IHC

    Name of antibody:

    UBXN1

    Immunogen:

    Full length fusion protein

    Full name:

    UBX domain protein 1

    Synonyms:

    2B28; SAKS1; UBXD10

    SwissProt:

    Q04323

    ELISA Recommended dilution:

    5000-10000

    IHC positive control:

    Human thyroid cancer and Human cervical cancer

    IHC Recommend dilution:

    40-200

    WB Predicted band size:

    33 kDa

    WB Positive control:

    Mouse brain tissue£¬Hela and HEPG2 cell lysates

    WB Recommended dilution:

    500-2000




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