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Background: |
Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion (By similarity). |
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Applications: |
ELISA, IHC |
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Name of antibody: |
FARP2 |
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Immunogen: |
Fusion protein of human FARP2 |
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Full name: |
FERM, ARH/RhoGEF and pleckstrin domain protein 2 |
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Synonyms: |
FIR; FRG; PLEKHC3 |
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SwissProt: |
O94887 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human thyroid cancer and Human liver cancer |
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IHC Recommend dilution: |
50-200 |
