购物车
帮助
021-54845833/15800441009
|
Background: |
This gene encodes a protein that is a component of the pancreas transcription factor 1 complex (PTF1) and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. The protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in this gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers. |
|
Applications: |
WB |
|
Name of antibody: |
PTF1A |
|
Immunogen: |
Fusion protein of human PTF1A |
|
Full name: |
pancreas specific transcription factor, 1a |
|
Synonyms: |
PACA; PAGEN2; bHLHa29; PTF1-p48 |
|
SwissProt: |
Q7RTS3 |
|
WB Predicted band size: |
35 KD |
|
WB Positive control: |
Mouse brain tissue, Rat brain tissue lysates |
|
WB Recommended dilution: |
200-1000 |
