购物车
帮助
021-54845833/15800441009
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Background: |
Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis By similarity. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling By similarity. |
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Applications: |
WB |
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Name of antibody: |
Fadd(Ab-191) |
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Immunogen: |
Synthesized peptide derived from C-terminal of human FADD. |
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Full name: |
Fas (TNFRSF6)-associated via death domain |
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Synonyms： |
GIG3; MORT1 |
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SwissProt: |
Q61160/Q13158 |
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WB Predicted band size: |
23 kDa |
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WB Positive control: |
A549 cells lysates |
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WB Recommended dilution: |
500-3000 |
