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中文名称：小鼠抗EIF4E单克隆抗体
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Background: |
The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. |
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Applications: |
WB |
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Name of antibody: |
EIF4E |
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Immunogen: |
Fusion protein of human EIF4E |
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Full name: |
eukaryotic translation initiation factor 4E |
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Synonyms: |
CBP; EIF4F; AUTS19; EIF4E1; eIF-4E; EIF4EL1 |
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SwissProt: |
P06730 |
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WB Predicted band size: |
25 kDa |
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WB Positive control: |
Jurkat, Hela, MCF7, K562, C6, 3T3, PC12, HepG2, CHO-K1, Raji, Raw264.7 and Ramos cell lysates |
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WB Recommended dilution: |
1000-5000 |
