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    ÖÐÎÄÃû³Æ£º Íÿ¹MSH4¶à¿Ë¡¿¹Ìå


    Ó¢ÎÄÃû³Æ£º Anti-MSH4 rabbit polyclonal antibody


    ¿¹      Ô­£º MSH4


    ´¢      ´æ£º Àä¶³£¨-20¡æ£©


    ËÞ      Ö÷£º Rabbit


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    ·´Ó¦ÖÖÊô£º Human, Mouse


    ±ê  ¼Ç  Î Unconjugate


    ¿Ë¡ÀàÐÍ£º rabbit polyclonal


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    Background:

    This gene encodes a member of the DNA mismatch repair mutS family. This member is a meiosis-specific protein that is not involved in DNA mismatch correction, but is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I. This protein and MSH5 form a heterodimer which binds uniquely to a Holliday Junction and its developmental progenitor, thus provoking ADP-ATP exchange, and stabilizing the interaction between parental chromosomes during meiosis double-stranded break repair.

    Applications:

    ELISA, IHC

    Name of antibody:

    MSH4

    Immunogen:

    Fusion protein of human MSH4

    Full name:

    mutS homolog 4

    SwissProt:

    O15457

    ELISA Recommended dilution:

    2000-5000

    IHC positive control:

    Human thyroid cancer and human brain

    IHC Recommend dilution:

    50-200




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