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021-54845833/15800441009
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Background: |
This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
ENO1 |
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Immunogen: |
Fusion protein of human ENO1 |
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Full name: |
enolase 1, (alpha) |
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Synonyms： |
NNE; PPH; MPB1; ENO1L1 |
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SwissProt: |
P06733 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human liver cancer and human thyroid cancer |
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IHC Recommend dilution: |
50-200 |
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WB Predicted band size: |
47 kDa |
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WB Positive control: |
Hela, A431 and hepG2 cells, mouse brain and liver tissue, mouse pancreas and human fetal brain tissue |
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WB Recommended dilution: |
500-2000 |
