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Ó¢ÎÄÃû³Æ£º Anti-PPP2R1B rabbit polyclonal antibody
±ð Ãû£º PR65B; PP2A-Abeta
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ËÞ Ö÷£º Rabbit
¿¹ Ô£º PPP2R1B
·´Ó¦ÖÖÊô£º Human
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
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Background: |
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described. |
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Applications: |
WB, IHC |
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Name of antibody: |
PPP2R1B |
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Immunogen: |
Synthesized peptide derived from internal of human PPP2R1B. |
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Full name: |
protein phosphatase 2, regulatory subunit A, beta |
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Synonyms£º |
PR65B; PP2A-Abeta |
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SwissProt: |
P30154 |
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IHC positive control: |
Human breast carcinoma tissue |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
66 kDa |
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WB Positive control: |
Jurkat cells and Hela cells lysates |
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WB Recommended dilution: |
500-3000 |


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