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ÖÐÎÄÃû³Æ£º INTS11 ¿¹Ô­£¨ÖØ×éµ°°×£©

Ó¢ÎÄÃû³Æ£º INTS11 Antigen (Recombinant Protein)

±ð    Ãû£º   integrator complex subunit 11; RC68; INT11; RC-68; CPSF3L; CPSF73L

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Fusion protein corresponding to a region derived from 401-600 amino acids of human INTS11

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Full name:

integrator complex subunit 11

Synonyms:

RC68; INT11; RC-68; CPSF3L; CPSF73L

Swissprot:

Q5TA45

Gene Accession:

BC013904

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of the Integrator complex (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]



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