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    ÖÐÎÄÃû³Æ£º  FCAR¿¹Ô­£¨ÖØ×éµ°°×£©

    Ó¢ÎÄÃû³Æ£º FCAR Antigen (Recombinant Protein)

    ±ð      Ãû£º CD89

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    Fusion protein corresponding to a region derived from 22-227 amino acids of human FCAR


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    Full name:

    Immunoglobulin alpha Fc receptor

    Synonyms:

    CD89

    Swissprot:

    P24071

    Gene Accession:

    BC027953

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.


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